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Adele Changoor

Assistant Professor/Staff Scientist

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Dr. Changoor completed her undergraduate degree in Biological Engineering at the University of Guelph followed by a Master’s degree where she performed biomechanical studies to evaluate equine subchondral bone lesion repair. She then completed a PhD at École Polytechnique Montreal in the laboratory of Michael Buschmann where she developed novel methods of cartilage evaluation that were used to evaluate a cartilage repair device, which is now approved for clinical use. During her postdoctoral fellowship she began to study electroarthrography, a non-invasive method for evaluating cartilage quality. She is now a staff scientist at the Lunenfeld-Tanenbaum Research Institute with a primary academic appointment in the Department of Surgery and does biomedical research in the areas of orthopaedics and arthritis.

Research Interests

Dr. Changoor's research centres on arthritis and articular joint repair, which represent growing burdens on publicly funded health care as the population ages. Her aims include improving detection of early arthritis to identify opportunities to intervene and delay disease progression, and exploring ways to increase osteochondral allograft transplantation, a surgical technique for cartilage repair that reduces the need for costlier total joint replacement.

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Publications

Changoor A, Garon M, Quenneville E, Bull SB, Gordon K, Savard P, Buschmann MD, Hurtig MB. Non-invasive electroarthrography measures load-induced cartilage streaming potentials via electrodes placed on skin surrounding an articular joint. Cartilage. 2020; doi.org/10.1177/1947603520928583.

Pilliar RM, Kandel RA, Grynpas MD, Theodoropoulos J, Hu Y, Allo B, Changoor A. Calcium polyphosphate particulates for bone void filler applications. Journal of Biomedical Materials Research. Part B, Applied Biomaterials. 2017; 105(4):874-84.

Méthot S, Changoor A, Tran-Khanh N, Hoemann CD, Stanish WD, Restrepo A, Shive MS, Buschmann MD. Osteochondral biopsy analysis demonstrates that BST-CarGel treatment improves structural and cellular characteristics of cartilage repair tissue compared with microfracture. Cartilage. 2015; 1947603515595837.

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